Chronic rhinosinusitis and olfaction after highly effective modulator therapy: The role of individual sinus inflammation-Reference-Cited by-同舟云学术

Chronic rhinosinusitis and olfaction after highly effective modulator therapy: The role of individual sinus inflammation

Published:2023-12-26 Issue: Volume: Page:
ISSN:2042-6976
Container-title:International Forum of Allergy & Rhinology
language:en
Short-container-title:Int Forum Allergy Rhinol

Author:

Miller Jessa E.¹^ORCID,Taylor‐Cousar Jennifer L.²,Humphries Stephen M.³^ORCID,Khatiwada Aastha⁴,Chen Haidee⁵,Wilson Alexandra⁶,Vladar Eszter K.⁷⁸,Lynch David A.³,Li Douglas A.⁹,Beswick Daniel M.¹^ORCID

Affiliation:

1. Department of Otolaryngology‐Head and Neck Surgery University of California Los Angeles California USA

2. Departments of Medicine and Pediatrics National Jewish Health Denver Colorado USA

3. Department of Radiology National Jewish Health Denver Colorado USA

4. Division of Biostatistics and Bioinformatics National Jewish Health Denver Colorado USA

5. David Geffen School of Medicine University of California Los Angeles California USA

6. Department of Clinical Research Services National Jewish Health Denver Colorado USA

7. Division of Pulmonary Sciences and Critical Care Medicine Department of Medicine University of Colorado School of Medicine Aurora Colorado USA

8. Department of Cell and Developmental Biology University of Colorado School of Medicine Aurora Colorado USA

9. Division of Pediatric Pulmonology University of California Los Angeles California USA

Abstract

Key Points

Individual sinus opacification (ISO) is measurable via a convolutional neural network approach.

ISO decreased through 2 years after highly effective modulator therapy was initiated.

In adults with cystic fibrosis, ISO did not correlate with quality of life or olfaction.

Funder

Cystic Fibrosis Foundation

Publisher

Wiley

Subject

Otorhinolaryngology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alr.23299

Reference10 articles.

1. Elexacaftor-Tezacaftor- Ivacaftor improves sinonasal outcomes in cystic fibrosis

2. Objective and patient‐based measures of chronic rhinosinusitis in people with cystic fibrosis treated with highly effective modulator therapy

3. Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele

4. Patient-reported outcome measures for adult chronic rhinosinusitis: A systematic review and quality assessment

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