Evaluation of Potential Drug‐Drug Interaction Risk of Pexidartinib With Substrates of Cytochrome P450 and P‐Glycoprotein-Reference-Cited by-同舟云学术

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Evaluation of Potential Drug‐Drug Interaction Risk of Pexidartinib With Substrates of Cytochrome P450 and P‐Glycoprotein

Published:2020-09-12 Issue:3 Volume:61 Page:298-306
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Zahir Hamim¹,Kobayashi Fumiaki²,Zamora Cynthia³,Gajee Roohi¹,Gordon Michael S.⁴,Babiker Hani M.⁵,Wang Qiang¹,Greenberg Jonathan¹,Wagner Andrew J.⁶

Affiliation:

1. Daiichi Sankyo Inc. Basking Ridge New Jersey USA

2. Daiichi Sankyo Co Ltd Tokyo Japan

3. Worldwide Clinical Trials San Antonio Texas USA

4. Honor Health Scottsdale Arizona USA

5. University of Arizona Cancer Center Tucson Arizona USA

6. Dana‐Farber Cancer Institute and Harvard Medical School Boston Massachusetts USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1734

Reference14 articles.

1. Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

2. Inhibition and Induction of Cytochrome P450 and the Clinical Implications

3. Mechanism-Based Inhibition of Cytochrome P450 3A4 by Therapeutic Drugs

4. Clinical consequences of polypharmacy in elderly

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Physiologically Based Pharmacokinetic Absorption Model for Pexidartinib to Evaluate the Impact of Meal Contents and Intake Timing on Drug Exposure;Clinical Pharmacology in Drug Development;2024-02-23

2. Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9;Advances in Pharmacological and Pharmaceutical Sciences;2023-12-01

3. The latest perspectives of small molecules FMS kinase inhibitors;European Journal of Medicinal Chemistry;2023-12

4. Dosing Recommendation Based on the Effects of Different Meal Types on Pexidartinib Pharmacokinetics in Healthy Subjects: Implementation of Model‐informed Drug Development Strategy;Clinical Pharmacology in Drug Development;2023-03-21

5. Role of CSF1R Inhibitor Pexidartinib for the Treatment of Cancer;Russian Journal of Bioorganic Chemistry;2022-12

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