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Decreased Drug Penetration in Inflamed Tissue Related to Changed Mucosal Metabolism in Experimental Colitis

  • Published:2007-08 Issue:8 Volume:96 Page:2145-2153
  • ISSN:0022-3549
  • Container-title:Journal of Pharmaceutical Sciences
  • language:en
  • Short-container-title:Journal of Pharmaceutical Sciences

Author:

Pellequer Yann,Weissenborn Verena,Lamprecht Alf

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference26 articles.

1. Drug therapy of inflammatory bowel disease;Egan;Drugs Today,1998

2. Carrier systems for the treatment of inflammatory bowel disease;Lamprecht;Drugs Future,2002

3. Experimental colitis increases small intestine permeability in the rat;Fries;Lab Invest,1999

4. Comparison of different measurements of intestinal permeability in inflammatory bowel disease;Howden;Am J Gastroenterol,1991

5. Assessing the site of increased intestinal permeability in coeliac and inflammatory bowel disease;Teahon;Gut,1996

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1. Bioadhesive pellets increase local 5-aminosalicylic acid concentration in experimental colitis;European Journal of Pharmaceutics and Biopharmaceutics;2012-06

2. Regulation of Drug Metabolizing Enzymes and Transporters in Infection, Inflammation, and Cancer;Encyclopedia of Drug Metabolism and Interactions;2012-01-31

3. Conventional Medical Management of Ulcerative Colitis: Tacrolimus;Crohn's Disease and Ulcerative Colitis;2011-11-02

4. Drug Delivery to the Colon;Controlled Release in Oral Drug Delivery;2011

5. Colonic delivery of carboxyfluorescein by pH-sensitive microspheres in experimental colitis;European Journal of Pharmaceutics and Biopharmaceutics;2010-10
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