Characterization of Physico-Mechanical Properties of Indomethacin and Polymers to Assess their Suitability for Hot-Melt Extrusion Processs as a Means to Manufacture Solid Dispersion/Solution**Mailing address of the place where the work was carried out, Hoffmann-La Roche, Inc., 340 Kingsland Street, Nutley, NJ, 07110.

Author:

Chokshi Rina J.,Sandhu Harpreet K.,Iyer Raman M.,Shah Navnit H.,Malick A.Waseem,Zia Hossein

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference21 articles.

1. Extrusion;Kruder,1985

2. Melt extrusion: from process to drug delivery technology;Breitenbach;European Journal of Pharmaceutics and Biopharmaceutics,2002

3. Preparation of extruded carbamazepine and PEG 4000 as a potential rapid release dosage form;Perissutti;European Journal of Pharmaceutics and Biopharmaceutics,2002

4. Evaluation of hot-melt extrusion as a new technique loading for the production of polymer based pellets for sustained release capsules containing high loading of freely soluble drugs;Follonier;Drug Development and Industrial Pharmacy,1994

5. Hot-melt extrusion process as a pharmaceutical process;McGinity;American Pharmaceutical Review,2001

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