Epileptic nystagmus as clinical manifestation of self‐limited focal epilepsy: Rethinking etiology and prognostic value and literature review

Abstract

AbstractEpileptic nystagmus (EN) is an uncommon ictal clinical manifestation characterized by rapid, repetitive eyeballs movements. Few cases of EN have been reported and, in most cases, electro‐clinical correlation showed a focal EEG activity, mainly in the occipital and temporo‐occipital areas. Although EN occurs both in idiopathic and non‐idiopathic epilepsy, the most frequent cause appears to be inborn or acquired alteration of brain structures. We report of a 12‐year‐old girl with EN as ictal manifestation of self‐limited focal seizures. We described clinical manifestations, electroencephalographic features, treatment, and follow‐up, presenting the ictal video‐EEG phenomenon. Alongside, we reviewed the reported clinical features of the few pediatric cases (seven patients) with idiopathic epileptic nystagmus through a systematic literature review. Isolated Epileptic Nystagmus (IEN) is much rarer than EN, as it is more frequently associated with other types of seizures, and can be idiopathic, especially in children. Epilepsy prognosis is usually favorable with appropriate treatment, and ASM discontinuation seems to be successful after few years of treatment.