Anti‐VEGF‐A therapy reduces lymphatic vessel density and expression of VEGFR‐3 in an orthotopic breast tumor model

Author:

Whitehurst Brandt1,Flister Michael J.1,Bagaitkar Juhi1,Volk Lisa1,Bivens Christopher M.1,Pickett Brent1,Castro‐Rivera Emely2,Brekken Rolf A.2,Gerard Robert D.3,Ran Sophia1

Affiliation:

1. Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL

2. Hamon Center for Therapeutic Oncology, University of Texas Southwestern Medical Center, Dallas, TX

3. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference66 articles.

1. Role of lymphangiogenic factors in tumor metastasis

2. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

3. Lymphatic vessels and lymphangiogenesis in female cancer: mechanisms, clinical impact and possible implications for anti‐lymphangiogenic therapies (review);Schoppmann SF;Oncol Rep,2002

4. Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes

5. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer;Beasley NJ;Cancer Res,2002

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