From On-Target to Off-Target Activity: Identification and Optimisation ofTrypanosoma bruceiGSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma bruceiDrug Discovery Lead Molecules-Reference-Cited by-同舟云学术

From On-Target to Off-Target Activity: Identification and Optimisation ofTrypanosoma bruceiGSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma bruceiDrug Discovery Lead Molecules

Published:2013-06-14 Issue:7 Volume:8 Page:1127-1137
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Woodland Andrew,Grimaldi Raffaella,Luksch Torsten,Cleghorn Laura A. T.,Ojo Kayode K.,Van Voorhis Wesley C.,Brenk Ruth,Frearson Julie A.,Gilbert Ian H.,Wyatt Paul G.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201300072/fullpdf

Reference50 articles.

1. Kinetoplastids: related protozoan pathogens, different diseases

2. Development of novel drugs for human African trypanosomiasis

3. The Atlas of human African trypanosomiasis: a contribution to global mapping of neglected tropical diseases

4. Drug resistance in Trypanosoma brucei spp., the causative agents of sleeping sickness in man and nagana in cattle

5. Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

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