Dual Inhibition of Pyruvate Dehydrogenase Complex and Respiratory Chain Complex Induces Apoptosis by a Mitochondria‐Targeted Fluorescent Organic Arsenical in vitro and in vivo-Reference-Cited by-同舟云学术

Dual Inhibition of Pyruvate Dehydrogenase Complex and Respiratory Chain Complex Induces Apoptosis by a Mitochondria‐Targeted Fluorescent Organic Arsenical in vitro and in vivo

Published:2020-03-18 Issue:6 Volume:15 Page:552-558
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Liu Yu‐Jiao¹^ORCID,Fan Xiao‐Yang¹,Zhang Dong‐Dong²,Xia Yin‐Zheng¹,Hu Yan‐Jun³,Jiang Feng‐Lei¹,Zhou Fu‐Ling²,Liu Yi¹³⁴

Affiliation:

1. Department of ChemistryWuhan University Wuhan 430072 China

2. Department of HaematologyZhongnan HospitalWuhan University Wuhan 430071 China

3. College of Chemistry and Materials ScienceNanning Normal University Nanning 530001 China

4. School of Chemistry and Chemical EngineeringWuhan University of Science and Technology Wuhan 430081 China

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900686

Reference64 articles.

2. History of the Development of Arsenic Derivatives in Cancer Therapy

3. Arsenic-Based Drugs: From Fowler’s Solution to Modern Anticancer Chemotherapy

4. How acute promyelocytic leukaemia revived arsenic

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