Identifying Small-Molecule Binding Sites for Epigenetic Proteins at Domain-Domain Interfaces-Reference-Cited by-同舟云学术

Identifying Small-Molecule Binding Sites for Epigenetic Proteins at Domain-Domain Interfaces

Published:2018-04-17 Issue:10 Volume:13 Page:1051-1057
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Bowkett David¹,Talon Romain¹,Tallant Cynthia¹,Schofield Chris²,von Delft Frank¹³⁴,Knapp Stefan¹⁵,Bruton Gordon⁶,Brennan Paul E.¹⁷^ORCID

Affiliation:

1. Structural Genomics Consortium (SGC) & Target Discovery Institute; Nuffield Department of Medicine; University of Oxford, NDM Research Building; Roosevelt Drive Oxford OX3 7FZ UK

2. Chemistry Research Laboratory; University of Oxford; Mansfield Road Oxford OX1 3TA UK

3. Diamond Light Source; Harwell Science and Innovation Campus Didcot OX11 0DE UK

4. Department of Biochemistry; University of Johannesburg; Auckland Park 2006 South Africa

5. Institute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences; Johann Wolfgang Goethe University; 60438 Frankfurt am Main Germany

6. GlaxoSmithKline; Medicines Research Centre; Gunnels Wood Road Stevenage Hertfordshire SG1 2NY UK

7. Alzheimer's Research (UK) Oxford Drug Discovery Institute; Nuffield Department of Medicine; University of Oxford, NDM Research Building; Roosevelt Drive Oxford OX3 7FZ UK

Funder

Wellcome Trust

H2020 European Research Council

AbbVie

Bayer

Boehringer Ingelheim

Canada Foundation for Innovation

Eshelman Institute for Innovation, University of North Carolina at Chapel Hill

Genome Canada

Janssen Pharmaceuticals

Merck

Merck KGaA