Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors-Reference-Cited by-同舟云学术

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors

Published:2015-10-23 Issue:12 Volume:10 Page:2042-2062
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

van den Berg Richard J. B. H. N.¹,van Rijssel Erwin R.¹,Ferraz Maria Joao¹,Houben Judith¹,Strijland Anneke²,Donker-Koopman Wilma E.²,Wennekes Tom¹³,Bonger Kimberly M.¹,Ghisaidoobe Amar B. T.¹,Hoogendoorn Sascha¹,van der Marel Gijsbert A.¹,Codée Jeroen D. C.¹,Overkleeft Herman S.¹,Aerts Johannes M. F. G.¹²

Affiliation:

1. Leiden Institute of Chemistry; Leiden University; Gorlaeus Laboratories; Einsteinweg 55 2300 RA Leiden The Netherlands

2. Department of Medical Biochemistry; Academic Medical Center; University of Amsterdam; Meibergdreef 9 1105 AZ Amsterdam The Netherlands

3. Laboratory of Organic Chemistry; Wageningen University; Dreijenplein 8 6703 HB Wageningen The Netherlands

Funder

Netherlands Organization for Scientific Research (NWO-CW)

European Research Council

ERC AdG ‘ChemBioSphing′

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference81 articles.

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3. Glycosphingolipide - Natur, Funktion und pharmakologische Modulierung

4. Glycosphingolipids and insulin resistance

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