Discovery and Structure–Activity Relationships of N ‐Aryl 6‐Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors-Reference-Cited by-同舟云学术

Discovery and Structure–Activity Relationships of N ‐Aryl 6‐Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors

Published:2018-12-06 Issue:1 Volume:14 Page:169-181
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Boutard Nicolas¹^ORCID,Białas Arkadiusz¹,Sabiniarz Aleksandra¹^ORCID,Guzik Paweł¹^ORCID,Banaszak Katarzyna¹,Biela Artur¹,Bień Marcin¹²,Buda Anna¹^ORCID,Bugaj Barbara¹,Cieluch Ewelina¹,Cierpich Anna¹³,Dudek Łukasz¹,Eggenweiler Hans‐Michael⁴^ORCID,Fogt Joanna¹^ORCID,Gaik Monika¹⁵,Gondela Andrzej¹,Jakubiec Krzysztof¹,Jurzak Mirek⁶,Kitlińska Agata¹,Kowalczyk Piotr¹^ORCID,Kujawa Maciej¹^ORCID,Kwiecińska Katarzyna¹⁷^ORCID,Leś Marcin¹,Lindemann Ralph⁸^ORCID,Maciuszek Monika¹⁹^ORCID,Mikulski Maciej¹^ORCID,Niedziejko Paulina¹^ORCID,Obara Alicja¹,Pawlik Henryk¹,Rzymski Tomasz¹,Sieprawska‐Lupa Magdalena¹,Sowińska Marta¹,Szeremeta‐Spisak Joanna¹^ORCID,Stachowicz Agata¹,Tomczyk Mateusz M.¹¹⁰^ORCID,Wiklik Katarzyna¹^ORCID,Włoszczak Łukasz¹¹¹^ORCID,Ziemiańska Sylwia¹,Zarębski Adrian¹,Brzózka Krzysztof¹,Nowak Mateusz¹^ORCID,Fabritius Charles‐Henry¹

Affiliation:

1. Selvita S.A. Bobrzyńskiego 14 30-348 Kraków Poland

2. Current address: Almac Group 20 Seagoe Industrial Estate Craigavon BT63 5QD UK

3. Current address: Grupa Azoty S.A. Kwiatkowskiego 8 33-100 Tarnów Poland

4. Medicinal Chemistry, Merck Biopharma Merck KGaA Frankfurter Straße 250 64293 Darmstadt Germany

5. Current address: Max Planck Research Group at the Małopolska Centre of Biotechnology Jagiellonian University Krakow Poland

6. Discovery Pharmacology, Merck Biopharma Merck KGaA Frankfurter Straße 250 64293 Darmstadt Germany

7. Current address: Captor Therapeutics Duńska 11 54-427 Wrocław Poland

8. Translational Innovation Platform Oncology, Merck Biopharma Merck KGaA Frankfurter Straße 250 64293 Darmstadt Germany

9. Current address: LifeArc Accelerator Building, Open Innovation Campus Stevenage SG1 2FX UK

10. Current address: Katedra Chemii Organicznej Bioorganicznej I Biotechnologii Ul. B. Krzywoustego 4, P., 18/N1 44-100 Gliwice Poland

11. Current address: Grupa Adamed Pieńków 149 05-152 Czosnów Poland

Funder

European Regional Development Fund

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201800569

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