Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)‐Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei

Author:

Cerone Michela12,Uliassi Elisa1,Prati Federica1,Ebiloma Godwin U.23,Lemgruber Leandro24,Bergamini Christian1,Watson David G.5,de A. M. Ferreira Thais6,Roth Cardoso Gabriella Simões Heyn6,Soares Romeiro Luiz A.6,de Koning Harry P.2,Bolognesi Maria Laura1ORCID

Affiliation:

1. Department of Pharmacy and BiotechnologyAlma Mater Studiorum – University of Bologna Via Belmeloro 6 40126 Bologna Italy

2. Institute of Infection, Immunity and InflammationUniversity of Glasgow GBRC, University Place G12 8AT Glasgow UK

3. Department of BiochemistryFaculty of Natural SciencesKogi State University P.M.B. 1008 Anyigba Kogi State Nigeria

4. Wellcome Trust Centre for Molecular ParasitologyInstitute of Infection, Immunity and InflammationUniversity of Glasgow GBRC, University Place G12 8AT Glasgow UK

5. Strathclyde Institute of Pharmacy and Biomedical SciencesUniversity of Strathclyde 16 Richmond Street G1 1XQ Glasgow UK

6. Department of Pharmacy, Health Sciences FacultyUniversity of Brasília Campus Universitário Darcy Ribeiro 70910-900 Brasília DF Brazil

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Università di Bologna

Tertiary Education Trust Fund

Wellcome Trust

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference66 articles.

1. Neglected Tropical Diseases World Health Organization:http://www.who.int/neglected_diseases/diseases/en/(accessed November 10 2018).

2.  

3. The Future of Drug Development for Neglected Tropical Diseases: How the European Commission Can Continue to Make a Difference

4. Increasing European Support for Neglected Infectious Disease Research

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