Synthesis and Biological Evaluation of RGD and iso DGR–Monomethyl Auristatin Conjugates Targeting Integrin α V β 3-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of RGD and iso DGR–Monomethyl Auristatin Conjugates Targeting Integrin α V β 3

Published:2019-03-22 Issue:9 Volume:14 Page:938-942
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Raposo Moreira Dias André¹^ORCID,Bodero Lizeth²^ORCID,Martins Ana³,Arosio Daniela⁴^ORCID,Gazzola Silvia²^ORCID,Belvisi Laura¹⁴^ORCID,Pignataro Luca¹^ORCID,Steinkühler Christian³,Dal Corso Alberto¹^ORCID,Gennari Cesare¹⁴^ORCID,Piarulli Umberto²^ORCID

Affiliation:

1. Università degli Studi di MilanoDipartimento di Chimica Via C. Golgi, 19 20133 Milan Italy

2. Università degli Studi dell'InsubriaDipartimento di Scienza e Alta Tecnologia Via Valleggio, 11 22100 Como Italy

3. Exiris Srl Via di Castel Romano, 100 00128 Rome Italy

4. CNRIstituto di Scienze e Tecnologie Molecolari (ISTM) Via C. Golgi, 19 20133 Milan Italy

Funder

H2020 Marie Skłodowska-Curie Actions

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900049

Reference76 articles.

2. The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

3. Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10

5. Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery: Effects of Linker Technology on Efficacy and Toxicity

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