Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity-Reference-Cited by-同舟云学术

Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity

Published:2016-12-15 Issue:1 Volume:12 Page:50-65
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Nordqvist Anneli¹^ORCID,O'Mahony Gavin¹,Fridén-Saxin Maria¹,Fredenwall Marlene¹,Hogner Anders¹,Granberg Kenneth L.¹,Aagaard Anna²,Bäckström Stefan²,Gunnarsson Anders²,Kaminski Tim²,Xue Yafeng²,Dellsén Anita²,Hansson Eva²,Hansson Pia²,Ivarsson Ida²,Karlsson Ulla²,Bamberg Krister¹,Hermansson Majlis¹,Georgsson Jennie¹,Lindmark Bo¹,Edman Karl²

Affiliation:

1. Cardiovascular and Metabolic Diseases; Innovative Medicines and Early Development Biotech Unit; AstraZeneca; Pepparedsleden 1 Mölndal 43183 Sweden

2. Discovery Sciences; Innovative Medicines and Early Development Biotech Unit; AstraZeneca; Pepparedsleden 1 43183 Mölndal Sweden

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference51 articles.

1. The Nuclear Receptor Superfamily and Drug Discovery

2. The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

3. Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction

4. Efficacy and tolerance of spironolactone in essential hypertension

5. Spironolactone, eplerenone and the new aldosterone blockers in endocrine and primary hypertension

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