Probing an Allosteric Pocket of CDK2 with Small Molecules-Reference-Cited by-同舟云学术

Probing an Allosteric Pocket of CDK2 with Small Molecules

Published:2016-12-19 Issue:1 Volume:12 Page:33-41
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Christodoulou Michael S.¹²,Caporuscio Fabiana¹,Restelli Valentina³,Carlino Luca¹,Cannazza Giuseppe¹,Costanzi Elisa⁴,Citti Cinzia⁵,Lo Presti Leonardo²,Pisani Pasquale¹,Battistutta Roberto⁴,Broggini Massimo³,Passarella Daniele²,Rastelli Giulio¹^ORCID

Affiliation:

1. Dipartimento di Scienze della Vita; Università degli Studi di Modena e Reggio Emilia; Via Campi 103 41125 Modena Italy

2. Dipartimento di Chimica; Università degli Studi di Milano; Via Golgi 19 20133 Milano Italy

3. Istituto di Ricerche Farmacologiche Mario Negri; Via La Masa 19 20156 Milano Italy

4. Dipartimento di Scienze Chimiche; Università degli Studi di Padova; Via Marzolo 1 35131 Padova Italy

5. Dipartimento di Scienze e Tecnologie Biologiche e Ambientali; Università del Salento; Via per Monteroni 73100 Lecce Italy

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference46 articles.

1. The changing landscape of protein allostery

2. Protein Kinase Inhibitors: Insights into Drug Design from Structure

3. Polypharmacology: Challenges and Opportunities in Drug Discovery

4. Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors

5. Discovery of a Potential Allosteric Ligand Binding Site in CDK2

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