Synthesis and Biological Evaluation of Imidazo[2,1-b][1,3,4]thiadiazole-Linked Oxindoles as Potent Tubulin Polymerization Inhibitors-Reference-Cited by-同舟云学术

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Synthesis and Biological Evaluation of Imidazo[2,1-b][1,3,4]thiadiazole-Linked Oxindoles as Potent Tubulin Polymerization Inhibitors

Published:2014-04-08 Issue:7 Volume:9 Page:1463-1475
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Kamal Ahmed,Rao M. P. Narasimha,Das Pompi,Swapna P.,Polepalli Sowjanya,Nimbarte Vijaykumar D.,Mullagiri Kishore,Kovvuri Jeshma,Jain Nishant

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201400069/fullpdf

Reference29 articles.

1. Levamisole: known effects on the immune system, clinical results, and future applications to the treatment of cancer.

2. Levamisole Potentiation of Fluorouracil Antiproliferative Activity Mimicked by Orthovanadate, an Inhibitor of Tyrosine Phosphatase

3. Levamisole Inhibits Angiogenesis in vitro and Tumor Growth in vivo

4. The effect of levamisole on energy metabolism in Ehrlich ascites tumour cells in vitro

5. Levamisole induced apoptosis in cultured vascular endothelial cells

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1. Regioselective synthesis and in vitro cytotoxicity evaluation of 3-thiooxindole derivatives: Tubulin polymerization inhibition and apoptosis inducing studies;Bioorganic & Medicinal Chemistry;2023-07

2. Mechanism-based approaches of 1,3,4 thiadiazole scaffolds as potent enzyme inhibitors for cytotoxicity and antiviral activity;Medicine in Drug Discovery;2023-02

3. Bicyclic 5-5 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Three Extra Heteroatoms 2:1;Comprehensive Heterocyclic Chemistry IV;2022

4. Thiadiazole derivatives as anticancer agents;Pharmacological Reports;2020-09-03

5. Novel imidazo[2,1-b][1,3,4]thiadiazole (ITD) hybrid compounds: Design, synthesis, efficient antibacterial activity and antioxidant effects;Bioorganic Chemistry;2019-08

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