Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ1γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone-Reference-Cited by-同舟云学术

Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ1γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone

Published:2016-09-13 Issue:20 Volume:11 Page:2299-2310
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Krall Jacob¹,Brygger Benjamin M.¹,Sigurðardóttir Sara B.¹,Ng Clarissa K. L.²,Bundgaard Christoffer³,Kehler Jan³,Nielsen Birgitte¹,Bek Toke⁴,Jensen Anders A.¹,Frølund Bente¹

Affiliation:

1. Department of Drug Design and Pharmacology; Faculty of Health and Medical Sciences; University of Copenhagen; Universitetsparken 2 2100 Copenhagen Denmark

2. School of Molecular, Genetic and Population Health Sciences; The University of Edinburgh; Crewe Road EH4 2XU Edinburgh UK

3. Discovery Chemistry and DMPK; H. Lundbeck A/S; Ottiliavej 9 2500 Valby Denmark

4. Department of Ophthalmology; Faculty of Health; Aarhus University; Nørrebrogade 44 8000 Aarhus Denmark

Funder

Danish Council for Independent Research

Lundbeck Foundation

Novo Nordisk Foundation

VELUX Foundation

Savvaerksejer Jeppe Juhl og hustru Ovita Juhls Mindelegat

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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