Synthesis and Pharmacological Properties of Silicon-Containing GPR81 and GPR109A Agonists-Reference-Cited by-同舟云学术

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Synthesis and Pharmacological Properties of Silicon-Containing GPR81 and GPR109A Agonists

Published:2015-10-13 Issue:12 Volume:10 Page:2063-2070
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Geyer Marcel¹,Baus Johannes A.¹,Fjellström Ola²,Wellner Eric²,Gustafsson Linda²,Tacke Reinhold¹^ORCID

Affiliation:

1. Universität Würzburg; Institut für Anorganische Chemie; Am Hubland 97074 Würzburg Germany

2. AstraZeneca R&D Mölndal; CVMD Innovative Medicines; Pepparedsleden 1 43183 Mölndal Sweden

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference35 articles.

1. Biological and Pharmacological Roles of HCA Receptors

2. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

3. Role of GPR81 in lactate-mediated reduction of adipose lipolysis

4. Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of silicon in drug discovery: a review;RSC Medicinal Chemistry;2024

2. A Theoretical Investigation of Novel Sila- and Germa-Spirocyclic Imines and Their Relevance for Electron-Transporting Materials and Drug Discovery;Molecules;2023-08-28

3. Lactate Metabolism and Signaling in Tuberculosis and Cancer: A Comparative Review;Frontiers in Cellular and Infection Microbiology;2021-02-26

4. Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation;Hypertension;2020-05

5. The roles of GRP81 as a metabolic sensor and inflammatory mediator;Journal of Cellular Physiology;2020-04-28

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