Identification of Compounds That Interfere with High‐Throughput Screening Assay Technologies-Reference-Cited by-同舟云学术

Identification of Compounds That Interfere with High‐Throughput Screening Assay Technologies

Published:2019-09-19 Issue:20 Volume:14 Page:1795-1802
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

David Laurianne¹²^ORCID,Walsh Jarrod³,Sturm Noé⁴,Feierberg Isabella⁵,Nissink J. Willem M.⁶,Chen Hongming¹,Bajorath Jürgen²,Engkvist Ola¹

Affiliation:

1. Hit Discovery, Discovery Sciences, R&D BioPharmaceuticalsAstraZeneca Goteborg Pepparedsleden 1 431 83 Mölndal Sweden

2. Department of Life Science Informatics, B-ITLIMES Program Unit Chemical Biology and Medicinal ChemistryRheinische Friedrich-Wilhelms-Universität Bonn Endenicher Allee 19c 53115 Bonn Germany

3. Hit Discovery, Discovery Sciences, R&D BioPharmaceuticalsAstraZeneca Cambridge Alderley Park Macclesfield SK10 4TG UK

4. Data Science and AI, Drug Safety & Metabolism, R&D BioPharmaceuticalsAstraZeneca Gothenburg Pepparedsleden 1 431 83 Mölndal Sweden

5. Hit Discovery, Discovery Sciences, R&D BioPharmaceuticalsAstraZeneca Boston 35 Gatehouse Drive Waltham MA 02451 USA

6. Computational Chemistry, Oncology R&DAstraZeneca Cambridge Science Park, Milton Road Cambridge CB4 0WG UK

Funder

H2020 Marie Skłodowska-Curie Actions

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900395

Reference38 articles.

1. High-throughput screening: new technology for the 21st century

2. Impact of high-throughput screening in biomedical research

3. The essential roles of chemistry in high-throughput screening triage

4. The importance of triaging in determining the quality of output from high-throughput screening

5. Comment on The Ecstasy and Agony of Assay Interference Compounds

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