Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential-Reference-Cited by-同舟云学术

Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential

Published:2016-08-25 Issue:21 Volume:11 Page:2378-2384
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Juhl Cathleen¹,Els-Heindl Sylvia²,Schönauer Ria²,Redlich Gorden³,Haaf Erik⁴,Wunder Frank⁵,Riedl Bernd¹,Burkhardt Nils⁵,Beck-Sickinger Annette G.²,Bierer Donald¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry; Bayer Pharma AG; Aprather Weg 18 A 42096 Wuppertal Germany

2. Institute of Biochemistry; Leipzig University; Brüderstraße 34 04103 Leipzig Germany

3. Global External Innovation & Alliances; Bayer Pharma AG; Aprather Weg 18 A 42096 Wuppertal Germany

4. Department of Pharmacokinetics and Metabolism; Bayer Pharma AG; Aprather Weg 18 A 42096 Wuppertal Germany

5. Lead Discovery Wuppertal; Bayer Pharma AG; Aprather Weg 18 A 42096 Wuppertal Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference78 articles.

1. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

2. Neuroprotection of apelin and its signaling pathway

3. Apelin/APJ system: a promising therapy target for hypertension

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