Roles of the Conserved Amino Acid Residues in Reduced Human Defensin 5: Cysteine and Arginine Are Indispensable for Its Antibacterial Action and LPS Neutralization-Reference-Cited by-同舟云学术

Roles of the Conserved Amino Acid Residues in Reduced Human Defensin 5: Cysteine and Arginine Are Indispensable for Its Antibacterial Action and LPS Neutralization

Published:2019-07-10 Issue:15 Volume:14 Page:1457-1465
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Chen Fang¹,Tang Yong¹,Zheng Hong²,Xu Yang¹,Wang Junping¹,Wang Cheng¹^ORCID

Affiliation:

1. State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury of PLA, Chongqing Engineering Research Center for Nanomedicine, College of Preventive MedicineThird Military Medical University Chongqing 400038 China

2. Department of Thoracic Surgery, Xinqiao HospitalThird Military Medical University Chongqing 400037 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900282

Reference63 articles.

1. Antimicrobial peptides of multicellular organisms

2. Antibacterial Activity and Specificity of the Six Human α-Defensins

3. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

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