Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action-Reference-Cited by-同舟云学术

Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action

Published:2019-04-24 Issue:11 Volume:14 Page:1074-1078
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Bongard Jens¹,Schmitz Anna Laura²,Wolf Alex³,Zischinsky Gunther³,Pieren Michel⁴,Schellhorn Birgit⁴,Bravo‐Rodriguez Kenny¹⁵,Schillinger Jasmin¹,Koch Uwe³,Nussbaumer Peter³,Klebl Bert³,Steinmann Jörg⁶⁷,Buer Jan⁶,Sanchez‐Garcia Elsa⁵,Ehrmann Michael¹,Kaiser Markus²^ORCID

Affiliation:

1. MicrobiologyFaculty of Biology, Center of Medical BiotechnologyUniversity Duisburg-Essen Universitätsstr. 2 45117 Essen Germany

2. Chemical BiologyFaculty of Biology, Center of Medical BiotechnologyUniversity Duisburg-Essen Universitätsstr. 2 45117 Essen Germany

3. Lead Discovery Center GmbH Otto-Hahn-Str. 15 44227 Dortmund Germany

4. BioVersys AG Hochbergerstrasse 60C 4057 Basel Switzerland

5. Computational Biochemistry, Faculty of Biology & Faculty of Chemistry, Center of Medical BiotechnologyUniversity Duisburg-Essen Universitätsstr. 2 45117 Essen Germany

6. University Hospital Essen, University of Duisburg-EssenInstitute of Medical Microbiology Hufelandstr. 55 45122 Essen Germany

7. Institute of Clinical Hygiene, Medical Microbiology and InfectiologyParacelsus Medical University Prof.-Ernst-Nathan-Straße 1 90419 Nürnberg Germany

Funder

Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900193

Reference36 articles.

2. Targeting Antibiotic Resistance

3. Antibiotikaresistenzen gezielt überwinden