Virtual Screening and Experimental Validation Identify Novel Inhibitors of thePlasmodium falciparumAtg8-Atg3 Protein-Protein Interaction-Reference-Cited by-同舟云学术

Virtual Screening and Experimental Validation Identify Novel Inhibitors of thePlasmodium falciparumAtg8-Atg3 Protein-Protein Interaction

Published:2016-01-08 Issue:8 Volume:11 Page:900-910
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Hain Adelaide U. P.¹,Miller Alexia S.²,Levitskaya Jelena³,Bosch Jürgen¹^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology; Johns Hopkins School of Public Health and; Johns Hopkins Malaria Research Institute; 615 N. Wolfe Street Baltimore MD 21205 USA

2. Department of Biophysics and Biophysical Chemistry; Johns Hopkins University School of Medicine; 725 N. Wolfe Street Baltimore MD 21205 USA

3. The W. Harry Feinstone Department of Molecular Microbiology and Immunology; Johns Hopkins Bloomberg School of Public Health; 615 N. Wolfe Street Baltimore MD 21205 USA

Funder

Johns Hopkins Malaria Research Institute (JHMRI)

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201500515/fullpdf

Reference59 articles.

1. Malaria Fact Sheet www.who.int/malaria/ 2015

2. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker

3. Epidemiology of and Diagnostic Strategies for Toxoplasmosis