In silico Screening and Evaluation ofPlasmodium falciparumProtein Kinase 5 (PK5) Inhibitors

Author:

Eubanks Amber L.1,Perkins Marisha M.1,Sylvester Kayla2,Ganley Jack G.1,Posfai Dora2,Sanschargrin Paul C.3,Hong Jiyong1,Sliz Piotr3,Derbyshire Emily R.12ORCID

Affiliation:

1. Department of ChemistryDuke University 124 Science Drive Durham NC 27708 USA

2. Department of Molecular Genetics and MicrobiologyDuke University Medical Center 213 Research Drive Durham NC 27710 USA

3. Department of Biological Chemistry and Molecular PharmacologyHarvard Medical School 45 Shattuck Street Boston MA 02115 USA

Funder

National Institute of General Medical Sciences

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference29 articles.

1. World Malaria Report 2017 World Health Organization 2017 ISBN: 978 924 1565523:http://www.who.int/malaria/publications/world-malaria-report-2017/report/en/(accessed October 30 2018).

2. The Threat of Artemisinin-Resistant Malaria

3. Artemisinin-Resistant Plasmodium falciparum Malaria

4. Protein kinases — the major drug targets of the twenty-first century?

5. Protein Kinases as Drug Targets in Cancer

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