Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor-Reference-Cited by-同舟云学术

Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor

Published:2018-08-01 Issue:17 Volume:13 Page:1806-1816
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Rappenglück Sebastian¹,Sichler Sonja¹,Höfner Georg¹,Wein Thomas¹,Niessen Karin V.²,Seeger Thomas²,Paintner Franz F.¹,Worek Franz²,Thiermann Horst²,Wanner Klaus T.¹^ORCID

Affiliation:

1. Department of Pharmacy, Center for Drug Research; Ludwig-Maximilians-Universität München; Butenandtstr. 5-13 81377 Munich Germany

2. Bundeswehr Institute of Pharmacology and Toxicology; Neuherbergstr. 11 80937 Munich Germany

Funder

German Ministry of Defense

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201800325/fullpdf

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1. The global distribution of fatal pesticide self-poisoning: Systematic review

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4. Nicotinic Antagonists in the Treatment of Nerve Agent Intoxication

5. Desensitization of nicotinic ACh receptors: shaping cholinergic signaling

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