Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins-Reference-Cited by-同舟云学术

Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins

Published:2016-06-07 Issue:13 Volume:11 Page:1469-1479
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Wu Yuet¹,Wu Ronald Wai Kung¹,Cheu Kwan Wing¹,Williams Ian D.¹,Krishna Sanjeev²,Slavic Ksenija²,Gravett Andrew M.³,Liu Wai M.³,Wong Ho Ning⁴¹,Haynes Richard K.⁴¹

Affiliation:

1. Department of Chemistry; The Hong Kong University of Science and Technology; Clear Water Bay Kowloon Hong Kong P.R. China

2. Centre for Infection; Division of Cellular and Molecular Medicine; St. George's Hospital; University of London; SW17 0RE UK

3. Department of Oncology; Division of Cellular and Molecular Medicine; St. George's Hospital; University of London; Jenner Wing London SW17 0RE UK

4. Centre of Excellence for Pharmaceutical Sciences; Faculty of Health Sciences; North-West University; Potchefstroom 2520 South Africa

Funder

Government of the HKSAR University Grants Committee Areas of Excellence Fund

University Grants Council

North-West University

South African Medical Research Council (MRC)

National Treasury

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference103 articles.

1. New medicines to improve control and contribute to the eradication of malaria

2. The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites

3. Artesunate and Dihydroartemisinin (DHA): Unusual Decomposition Products Formed under Mild Conditions and Comments on the Fitness of DHA as an Antimalarial Drug

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