Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype Activity-Reference-Cited by-同舟云学术

Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype Activity

Published:2013-10-14 Issue:12 Volume:8 Page:1930-1940
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Coburn Craig A.,Meinke Peter T.,Chang Wei,Fandozzi Christine M.,Graham Donald J.,Hu Bin,Huang Qian,Kargman Stacia,Kozlowski Joseph,Liu Rong,McCauley John A.,Nomeir Amin A.,Soll Richard M.,Vacca Joseph P.,Wang Dahai,Wu Hao,Zhong Bin,Olsen David B.,Ludmerer Steven W.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference24 articles.

1. Evolving epidemiology of hepatitis C virus

2. Understanding the hepatitis C virus life cycle paves the way for highly effective therapies

3. Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life

4. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

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