Synthesis and Biological Evaluation of Novel Epothilone B Side Chain Analogues-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of Novel Epothilone B Side Chain Analogues

Published:2015-10-08 Issue:12 Volume:10 Page:1974-1979
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Nicolaou K. C.¹,Rhoades Derek¹²,Wang Yanping¹,Totokotsopoulos Sotirios¹³,Bai Ruoli⁴,Hamel Ernest⁴

Affiliation:

1. Department of Chemistry; Rice University; 6100 Main Street Houston TX 77005 USA

2. Department of Chemistry & Biochemistry; University of California, San Diego; 9500 Gilman Drive La Jolla CA 92093 USA

3. Department of Chemistry; The Scripps Research Institute; 10550 North Torrey Pines Road La Jolla CA 92037 USA

4. Screening Technologies Branch, Developmental Therapeutics Program; Division of Cancer Treatment and Diagnosis; Frederick National Laboratory for Cancer Research; National Cancer Institute; National Institutes of Health; Frederick MD 21702 USA

Funder

Cancer Prevention & Research Institute of Texas (CPRIT)

Welch Foundation

Bristol-Myers Squibb

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201500401/fullpdf

Reference60 articles.

1. Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

2. Epothilon A und B – neuartige, 16gliedrige Makrolide mit cytotoxischer Wirkung: Isolierung, Struktur im Kristall und Konformation in Lösung

3. The Olefin Metathesis Approach to Epothilone A and Its Analogues

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