Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity-Reference-Cited by-同舟云学术

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity

Published:2016-01-11 Issue:3 Volume:11 Page:331-339
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Landge Sudhir¹,Ramachandran Vasanthi¹,Kumar Anupriya¹,Neres João²,Murugan Kannan¹,Sadler Claire³,Fellows Mick D.³,Humnabadkar Vaishali¹,Vachaspati Prakash¹,Raichurkar Anandkumar¹,Sharma Sreevalli¹,Ravishankar Sudha¹,Guptha Supreeth¹,Sambandamurthy Vasan K.¹,Balganesh Tanjore S.¹,Ugarkar Bheemarao G.¹,Balasubramanian V.¹,Bandodkar Balachandra S.¹,Panda Manoranjan¹⁴

Affiliation:

1. iMED Infection; AstraZeneca India Pvt. Ltd.; Bellary Road, Hebbal Bangalore 560024 India

2. Global Health Institute; École Polytechnique Fédérale de Lausanne (EPFL); 1015 Lausanne Switzerland

3. iMED Safety Assessment; AstraZeneca; Alderley Park Macclesfield SK10 4TF UK

4. Biocon Bristol-Myers Squibb Research Center; Biocon Park; Jigani Link Road Bangalore 560099 India

Funder

New Medicines for Tuberculosis (NM4TB) Consortium

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201500462/fullpdf

Reference68 articles.

1. Mutagenicity of Nitroaromatic Compounds

2. A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds

3. Lessons from Seven Decades of Antituberculosis Drug Discovery

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