Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist-Reference-Cited by-同舟云学术

Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist

Published:2016-11-15 Issue:3 Volume:12 Page:197-201
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Orain David¹,Tasdelen Engin¹,Haessig Samuel¹,Koller Manuel¹,Picard Anne¹,Dubois Celine¹,Lingenhoehl Kurt²,Desrayaud Sandrine³,Floersheim Phillip¹,Carcache David¹,Urwyler Stephan²,Kallen Joerg⁴,Mattes Henri¹^ORCID

Affiliation:

1. Global Discovery Chemistry; Novartis Institute for Biomedical Research; 4002 Basel Switzerland

2. Previously: Neuroscience Disease Area; Novartis Institute for Biomedical Research; 4002 Basel Switzerland

3. Metabolism and Pharmacokinetics; Novartis Institute for Biomedical Research; 4002 Basel Switzerland

4. Center for Proteomic Chemistry; Novartis Institute for Biomedical Research; 4002 Basel Switzerland

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference41 articles.

1. Early Identification of Refractory Epilepsy

2. The impact of epilepsy from the patient’s perspective I. Descriptions and subjective perceptions

3. The impact of epilepsy from the patient’s perspective II: views about therapy and health care

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