11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α‐Synuclein Fibrils in vitro and Crosses the Blood‐Brain Barrier-Reference-Cited by-同舟云学术

11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α‐Synuclein Fibrils in vitro and Crosses the Blood‐Brain Barrier

Published:2020-01-09 Issue:5 Volume:15 Page:411-415
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Maurer Andreas¹^ORCID,Leonov Andrei²³,Ryazanov Sergey²,Herfert Kristina¹^ORCID,Kuebler Laura¹,Buss Sabrina¹,Schmidt Felix⁴,Weckbecker Daniel⁴,Linder Ruth²,Bender Dirk⁵,Giese Armin⁴³^ORCID,Pichler Bernd J.¹^ORCID,Griesinger Christian²³^ORCID

Affiliation:

1. Werner Siemens Imaging Center, Department of Preclinical Imaging and RadiopharmacyEberhard Karls University Tübingen Röntgenweg 15 72076 Tübingen Germany

2. Department of NMR-based Structural BiologyMax Planck Institute for Biophysical Chemistry Am Fassberg 11 37077 Göttingen Germany

3. MODAG GmbH Mikro-Forum-Ring 3 55234 Wendelsheim Germany

4. Center for Neuropathology and Prion ResearchLudwig Maximilians University Feodor-Lynen-Str. 23 81377 Munich Germany

5. Department for Nuclear Medicine and PET CenterAarhus University Hospital Palle Juul-Jensens Boulevard 165 8200 Aarhus Denmark

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900689

Reference23 articles.

1. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

2. Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

3. α-synuclein Imaging: A Critical Need for Parkinson's Disease Research

4. α-Synucleinopathy phenotypes

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