Breakdown Kinetics of C-Hydroxymethyl β-Dicarbonyl Derivatives of Carbon Acids: Implications in the Bioconversion Rate of C-Phosphoryloxymethyl Prodrugs of Carbon Acids

Author:

Dhareshwar Sundeep S.,Stella Valentino J.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference31 articles.

1. Phosphoryloxymethyl/(oxymethyl) prodrugs of ß-dicarbonyl carbon acid drugs;Dhareshwar,2007

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3. Human placental alkaline phosphatase in liver and intestine;Garattini;Proc Natl Acad Sci USA,1985

4. Stereochemical, mechanistic, and structural features of enzyme-catalyzed phosphate monoester hydrolyses;Gani;Chem Soc Rev,1995

5. Fundamentals of carbanion chemistry (organic chemistry, Vol 4);Cram,1965

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