A Novel Peptide Derived From Tissue-Type Plasminogen Activator Potently Inhibits Angiogenesis and Corneal Neovascularization

Author:

Kim Hyun-Kyung123,Choi Jun-Sub4,Lee Seung Woo123,Joo Choun-Ki4,Joe Young Ae123

Affiliation:

1. Cancer Research Institute; College of Medicine; The Catholic University of Korea; Seoul Republic of Korea

2. Department of Medical Lifescience; College of Medicine; The Catholic University of Korea; Seoul Republic of Korea

3. Cancer Evolution Research Center; College of Medicine; The Catholic University of Korea; Seoul Republic of Korea

4. Department of Ophthalmology and Visual Science; College of Medicine; The Catholic University of Korea; Seoul Republic of Korea

Funder

National Research Foundation of Korea

Ministry of Health, Welfare and Family Affairs

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference46 articles.

1. Effect of bevacizumab on corneal neovascularization in experimental rabbit model;Ahmed;Clin Exp Ophthalmol,2009

2. Corneal angiogenic privilege: Angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological Society thesis);Azar;Trans Am Ophthalmol Soc,2006

3. Promotion of graft survival by vascular endothelial growth factor a neutralization after high-risk corneal transplantation;Bachmann;Arch Ophthalmol,2008

4. Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug;Byeon;J Mol Biol,1991

5. Molecular basis of angiogenesis. Role of VEGF and VE-cadherin;Carmeliet;Ann NY Acad Sci,2000

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