Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality-Reference-Cited by-同舟云学术

Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality

Published:2021-07-31 Issue:11 Volume:118 Page:4305-4316
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotech & Bioengineering

Author:

Lee Alison P.¹^ORCID,Kok Yee Jiun¹,Lakshmanan Meiyappan¹,Leong Dawn¹,Zheng Lu¹,Lim Hsueh Lee¹,Chen Shuwen¹,Mak Shi Ya¹,Ang Kok Siong¹,Templeton Neil²^ORCID,Salim Taha³,Wei Xiaona⁴,Gifford Eric⁴,Tan Andy Hee‐Meng¹,Bi Xuezhi¹⁵^ORCID,Ng Say Kong¹,Lee Dong‐Yup¹⁶^ORCID,Ling Wai Lam W.³,Ho Ying Swan¹^ORCID

Affiliation:

1. Bioprocessing Technology Institute, Agency for Science Technology and Research (A*STAR) Singapore Singapore

2. Process Research and Development Merck & Co. Inc. West Point Pennsylvania USA

3. Process Research and Development Merck & Co. Inc. Kenilworth New Jersey USA

4. Scientific Informatics MSD International GmbH (Singapore Branch) Singapore Singapore

5. Duke‐NUS Medical School Singapore Singapore

6. School of Chemical Engineering Sungkyunkwan University Seoul Gyeonggi‐do Republic of Korea

Funder

Biomedical Research Council

Merck

Publisher

Wiley