A Novel AKR1C3 Specific Prodrug TH3424 With Potent Antitumor Activity in Liver Cancer

Author:

He Ping12,Wang Chunnian3,Wang Yanlan12,Wang Caiyan4,Zhou Changhua12,Cao Donglin5,Li Jiang6,Bushnell David A.7,Li Qing12,Kornberg Roger D.27,Xie Wei28,Wang Zhong12

Affiliation:

1. School of Pharmaceutical Sciences Sun Yat‐Sen University Guangzhou China

2. Centre for Cellular & Structural Biology Sun Yat‐Sen University Guangzhou China

3. Shanghai Institute for Advanced Immunochemical Studies Shanghai Tech University Shanghai China

4. International Institute for Translational Chinese Medicine Guangzhou University of Chinese Medicine Guangzhou China

5. Department of Laboratory Medicine Guangdong No. 2 Provincial People’s Hospital Guangzhou China

6. State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Sun Yat‐Sen University Guangzhou China

7. Department of Structural Biology Stanford University Stanford California USA

8. MOE Key Laboratory of Gene Function and Regulation School of Life Sciences Sun Yat‐Sen University Guangzhou China

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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