Multicenter propensity score‐matched analysis comparing short versus long cap‐assisted colonoscopy for acute hematochezia

Author:

Kobayashi Mariko1,Akiyama Shintaro2ORCID,Narasaka Toshiaki12ORCID,Kobayashi Katsumasa3,Yamauchi Atsushi4ORCID,Yamada Atsuo5ORCID,Omori Jun6,Ikeya Takashi7,Aoyama Taiki8ORCID,Tominaga Naoyuki9,Sato Yoshinori10ORCID,Kishino Takaaki11,Ishii Naoki12,Sawada Tsunaki13ORCID,Murata Masaki14,Takao Akinari15,Mizukami Kazuhiro16ORCID,Kinjo Ken17,Fujimori Shunji18,Uotani Takahiro19,Fujita Minoru20,Sato Hiroki21,Suzuki Sho22ORCID,Hayasaka Junnosuke23ORCID,Funabiki Tomohiro2425,Kinjo Yuzuru26,Mizuki Akira27,Kiyotoki Shu28,Mikami Tatsuya29,Gushima Ryosuke30,Fujii Hiroyuki31,Fuyuno Yuta32,Gunji Naohiko33,Toya Yosuke34ORCID,Narimatsu Kazuyuki35,Manabe Noriaki36ORCID,Nagaike Koji37,Kinjo Tetsu38,Sumida Yorinobu39,Funakoshi Sadahiro40ORCID,Kobayashi Kiyonori41ORCID,Matsuhashi Tamotsu42,Komaki Yuga43,Tsuchiya Kiichiro2,Kaise Mitsuru6,Nagata Naoyoshi4445ORCID

Affiliation:

1. Division of Endoscopic Center University of Tsukuba Hospital Tsukuba Japan

2. Department of Gastroenterology University of Tsukuba Tsukuba Japan

3. Department of Gastroenterology Tokyo Metropolitan Bokutoh Hospital Tokyo Japan

4. Department of Gastroenterology and Hepatology Kitano Hospital, Tazuke Kofukai Medical Research Institute Osaka Japan

5. Department of Gastroenterology Graduate School of Medicine, The University of Tokyo Tokyo Japan

6. Department of Gastroenterology Nippon Medical School, Graduate School of Medicine Tokyo Japan

7. Department of Gastroenterology St. Luke's International University Tokyo Japan

8. Department of Gastroenterology Hiroshima City Asa Citizens Hospital Hiroshima Japan

9. Department of Gastroenterology Saga‐Ken Medical Centre Koseikan Saga Japan

10. Division of Gastroenterology and Hepatology, Department of Internal Medicine St Marianna University School of Medicine Kawasaki Japan

11. Department of Gastroenterology and Hepatology, Center for Digestive and Liver Diseases Nara City Hospital Nara Japan

12. Department of Gastroenterology Tokyo Shinagawa Hospital Tokyo Japan

13. Department of Endoscopy Nagoya University Hospital Nagoya Japan

14. Department of Gastroenterology National Hospital Organization Kyoto Medical Center Kyoto Japan

15. Department of Gastroenterology Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Tokyo Japan

16. Department of Gastroenterology Oita University Oita Japan

17. Department of Gastroenterology Fukuoka University Chikushi Hospital Fukuoka Japan

18. Department of Gastroenterology Chiba Hokusoh Hospital, Nippon Medical School Chiba Japan

19. Department of Gastroenterology Japanese Red Cross Shizuoka Hospital Shizuoka Japan

20. Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine Kawasaki Medical School General Medical Center Okayama Japan

21. Division of Gastroenterology Graduate School of Medical and Dental Sciences, Niigata University Niigata Japan

22. Department of Gastroenterology and Hepatology, Center for Digestive Disease and Division of Endoscopy University of Miyazaki Hospital Miyazaki Japan

23. Department of Gastroenterology Toranomon Hospital Tokyo Japan

24. Department of Emergency Medicine Fujita Health University Hospital Toyoake Japan

25. Emergency and Critical Care Center Saiseikai Yokohama Tobu Hospital Yokohama Japan

26. Department of Gastroenterology Naha City Hospital Naha Japan

27. Department of Internal Medicine Tokyo Saiseikai Central Hospital Tokyo Japan

28. Department of Gastroenterology Shuto General Hospital Yanai‐shi Japan

29. Division of Endoscopy Hirosaki University Hospital Hirosaki Japan

30. Department of Gastroenterology and Hepatology Graduate School of Medical Sciences, Kumamoto University Kumamoto Japan

31. Department of Gastroenterology and Hepatology National Hospital Organization Fukuokahigashi Medical Center Koga Japan

32. Department of Medicine and Clinical Science Graduate School of Medical Sciences, Kyushu University Fukuoka Japan

33. Department of Gastroenterology Fukushima Medical University Fukushima Japan

34. Division of Gastroenterology, Department of Internal Medicine Iwate Medical University Morioka Japan

35. Department of Internal Medicine National Defense Medical College Tokorozawa Japan

36. Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine Kawasaki Medical School Kurashiki Japan

37. Department of Gastroenterology and Hepatology Suita Municipal Hospital Suita Japan

38. Department of Endoscopy University of the Ryukyus Hospital Nishihara Japan

39. Department of Gastroenterology National Hospital Organization Kyushu Medical Center Fukuoka Japan

40. Department of Gastroenterological Endoscopy Fukuoka University Hospital Fukuoka Japan

41. Department of Gastroenterology Kitasato University, School of Medicine Sagamihara Japan

42. Department of Gastroenterology and Neurology Akita University Graduate School of Medicine Akita Japan

43. Digestive and Lifestyle Diseases, and Hygiene and Health Promotion Medicine Kagoshima University Graduate School of Medical and Dental Sciences Kagoshima Japan

44. Department of Gastroenterological Endoscopy Tokyo Medical University Tokyo Japan

45. Department of Gastroenterology and Hepatology National Center for Global Health and Medicine Tokyo Japan

Abstract

AbstractBackground and AimWhile short and long attachment caps are available for colonoscopy, it is unclear which type is more appropriate for stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the performance of short versus long caps in acute hematochezia diagnoses and outcomes.MethodsWe selected 6460 patients who underwent colonoscopy with attachment caps from 10 342 acute hematochezia cases in the CODE BLUE‐J study. We performed propensity score matching (PSM) to balance baseline characteristics between short and long cap users. Then, the proportion of definitive or presumptive bleeding etiologies found on the initial colonoscopy and SRH identification rates were compared. We also evaluated rates of blood transfusions, interventional radiology, or surgery, as well as the rate of rebleeding and mortality within 30 days after the initial colonoscopy.ResultsA total of 3098 patients with acute hematochezia (1549 short cap and 1549 long cap users) were selected for PSM. The rate of colonic diverticular bleeding (CDB) diagnosis was significantly higher in long cap users (P = 0.006). While the two groups had similar rates of the other bleeding etiologies, the frequency of unknown etiologies was significantly lower in long cap users (P < 0.001). The rate of SRH with active bleeding was significantly higher in long cap users (P < 0.001). Other clinical outcomes did not differ significantly.ConclusionCompared to that with short caps, long cap‐assisted colonoscopy is superior for the diagnosis of acute hematochezia, especially CDB, and the identification of active bleeding.

Funder

Smoking Research Foundation

Takeda Science Foundation

Publisher

Wiley

Subject

Gastroenterology,Hepatology

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