Current otolaryngologic applications of the novel self‐assembling <scp>RADA</scp>‐16 peptide matrix-Reference-Cited by-同舟云学术

Current otolaryngologic applications of the novel self‐assembling RADA‐16 peptide matrix

Published:2024-07-16 Issue:4 Volume:9 Page:
ISSN:2378-8038
Container-title:Laryngoscope Investigative Otolaryngology
language:en
Short-container-title:Laryngoscope Investig Oto

Author:

Pak Kaitlynne Y.¹^ORCID,Tang Dennis M.¹,Sreenath Satyan B.²,Ito Christopher J.³^ORCID,Senior Brent A.⁴,Lam Kent K.⁵^ORCID,Higgins Thomas S.⁶^ORCID,Hur Kevin⁷,Tam Benjamin⁷^ORCID,Khalid Ayesha N.⁸,Wu Arthur W.¹^ORCID

Affiliation:

1. Division of Otolaryngology‐Head & Neck Surgery Cedars‐Sinai Medical Center Los Angeles USA

2. Department of Otolaryngology‐Head & Neck Surgery Indiana University Bloomington USA

3. Department of Otolaryngology‐Head & Neck Surgery University of Massachusetts Amherst USA

4. Department of Otolaryngology‐Head & Neck Surgery University of North Carolina Chapel Hill USA

5. Department of Otolaryngology‐Head & Neck Surgery Eastern Virginia Medical School Norfolk UK

6. Department of Otolaryngology‐Head & Neck Surgery University of Louisville Louisville USA

7. Department of Otolaryngology‐Head & Neck Surgery University of Southern California Los Angeles USA

8. Division of Otolaryngology‐Head & Neck Surgery Harvard Medical School and Cambridge Health Alliance Boston USA

Abstract

A novel bioresorbable agent on the market is PuraGel® (3‐D Matrix, Tokyo, Japan), a RADA‐16 product that acts as a synthetic hemostatic and space‐filling gel that promotes wound healing and prevents adhesion formation. Given the reported benefits of accelerated wound healing and scar tissue prevention, there are multiple otolaryngologic applications where RADA‐16 might improve outcomes. Our study highlights current utilization and associated post‐operative complications with this product.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/lio2.1299

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