All-trans retinoic acid-induced ectopic limb and caudal structures: Murine strain sensitivities and pathogenesis
Author:
Publisher
Wiley
Subject
Developmental Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/dvdy.21568/fullpdf
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1. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures
2. Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1
3. Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation
4. The organizer factors Chordin and Noggin are required for mouse forebrain development
5. Induction of a second neural axis by the mouse node
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