MicroRNAs as regulators of beta-cell function and dysfunction

Author:

Osmai Mirwais1,Osmai Yama1,Bang-Berthelsen Claus H.23,Pallesen Emil M. H.1,Vestergaard Anna L.1,Novotny Guy W.1,Pociot Flemming2,Mandrup-Poulsen Thomas14

Affiliation:

1. Immuno-endocrinology Lab, Section of Endocrinological Research, Department of Biomedical Sciences, Panum Institute; University of Copenhagen; Copenhagen Denmark

2. Department of Pediatrics and Center for Non-Coding RNA in Technology and Health, Herlev Hospital; University of Copenhagen; Copenhagen Denmark

3. Diabetes NBEs and Obesity Biology; Novo Nordisk A/S; Måløv Denmark

4. Department of Molecular Medicine and Surgery; Karolinska Institutet; Stockholm Sweden

Funder

Danish Strategic Research Council

Danish Research Agency

Novo Nordisk Foundation

European Communities Seventh Framework Programme

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference115 articles.

1. Beta cell 5′-shifted isomiRs are candidate regulatory hubs in type 2 diabetes;Baran-Gale;PLoS One,2013

2. Human beta cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes;Moran;Cell Metab,2012

3. The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis;Bunt;PLoS One,2013

4. Non-coding RNAs in human disease;Esteller;Nat Rev Genet,2011

5. Natural RNA circles function as efficient microRNA sponges;Hansen;Nature,2013

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