Conditional Deletion of <scp>HIF</scp> ‐2α in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age‐Dependent Structural Changes in Intervertebral Disc-Reference-Cited by-同舟云学术

Conditional Deletion of HIF ‐2α in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age‐Dependent Structural Changes in Intervertebral Disc

Published:2022-10-12 Issue:12 Volume:37 Page:2512-2530
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J of Bone & Mineral Res

Author:

Johnston Shira N¹²^ORCID,Madhu Vedavathi²,Shapiro Irving M²,Risbud Makarand V¹²^ORCID

Affiliation:

1. Graduate Program in Cell Biology and Regenerative Medicine Thomas Jefferson University Philadelphia PA USA

2. Department of Orthopaedic Surgery Thomas Jefferson University Philadelphia PA USA

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute on Aging

University of Michigan

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbmr.4707

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4. Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc

5. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.

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