Application of the adverse outcome pathway framework to genotoxic modes of action-Reference-Cited by-同舟云学术

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Application of the adverse outcome pathway framework to genotoxic modes of action

Published:2019-10-31 Issue:1 Volume:61 Page:114-134
ISSN:0893-6692
Container-title:Environmental and Molecular Mutagenesis
language:en
Short-container-title:Environ Mol Mutagen

Author:

Sasaki Jennifer C.¹,Allemang Ashley²^ORCID,Bryce Steven M.³,Custer Laura⁴,Dearfield Kerry L.⁵,Dietz Yasmin⁶,Elhajouji Azeddine⁷,Escobar Patricia A.⁸,Fornace Albert J.⁹,Froetschl Roland¹⁰^ORCID,Galloway Sheila⁸,Hemmann Ulrike⁶,Hendriks Giel¹¹,Li Heng‐Hong⁹,Luijten Mirjam¹²,Ouedraogo Gladys¹³,Peel Lauren¹⁴,Pfuhler Stefan²,Roberts Daniel J.¹⁵,Thybaud Véronique¹⁶,Benthem Jan¹²,Yauk Carole L.¹⁷,Schuler Maik¹⁸

Affiliation:

1. Genentech, Inc. South San Francisco California

2. Procter & Gamble Mason Ohio

3. Litron Laboratories Rochester New York

4. Bristol‐Myers Squibb Company, Drug Safety Evaluation New Brunswick New Jersey

5. Burke Virginia

6. Sanofi‐Aventis Deutschland GmbH Frankfurt Germany

7. Novartis Pharma AG Basel Switzerland

8. Merck &Co. Inc. West Point Pennsylvania

9. Georgetown University Washington District of Columbia

10. Federal Institute for Drugs and Medical Devices Bonn Germany

11. Toxys Leiden The Netherlands

12. National Institute for Public Health and the Environment Bilthoven The Netherlands

13. L'oréal Recherche & Innovation Aulnay‐Sous‐Bois France

14. Health and Environmental Sciences Institute Washington District of Columbia

15. Charles River Laboratoires Skokie Illinois

16. Sanofi, Research and Development, Preclinical Safety Vitry‐sur‐Seine France

17. Environmental Health Science and Research Bureau, Health Canada Ottawa Ontario Canada

18. Pfizer Inc World Wide Research and Development Groton, Connecticut

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.22339

Reference164 articles.

1. Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

2. Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

3. Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition

4. Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

5. Suppression of mismatched mutation by p53: a mechanism for guarding genomic integrity

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