BACE1 RNA interference improves spatial memory and attenuates Aβburden in a streptozotocin-induced tau hyperphosphorylated rat model-Reference-Cited by-同舟云学术

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BACE1 RNA interference improves spatial memory and attenuates Aβburden in a streptozotocin-induced tau hyperphosphorylated rat model

Published:2014-09-17 Issue:7 Volume:32 Page:590-596
ISSN:0263-6484
Container-title:Cell Biochemistry and Function
language:en
Short-container-title:Cell Biochem Funct

Author:

Yu Chun-Jiang¹,Liu Wei²,Chen Hong-Yuan¹,Wang Li³,Zhang Zhi-Ren⁴

Affiliation:

1. Department of Neurology; Second Affiliated Hospital of Harbin Medical University; Harbin Heilongjiang China

2. Department of Neurology; Haidian Hospital; Beijing 100080 China

3. Department of Geriatrics; Second Affiliated Hospital of Harbin Medical University; Harbin Heilongjiang China

4. Department of Pharmacy; Second Affiliated Hospital of Harbin Medical University; Harbin Heilongjiang China

Funder

Natural Science Foundation of Heilongjiang Province of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,General Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbf.3055/fullpdf

Reference39 articles.

1. Amyloid beta peptide load is correlated with increased b-secretase activity in sporadic Alzheimer's disease patients;Li;Proc Natl Acad Sci U S A,2004

2. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor;Hong;Science,2000

3. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA;Tiscornia;Proc Natl Acad Sci U S A,2003

4. In vivo gene delivery and stable transduction of non-dividing cells by a lentiviral vector;Naldini;Science,1996

5. BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease;Ohno;Neuron,2004

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1. Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease;Acta Pharmaceutica Sinica B;2019-05

2. cPLA2 and desaturases underlie the tau hyperphosphorylation offset induced by BACE knock-down in neuronal primary cultures;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2018-11

3. Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease;Journal of Controlled Release;2018-06

4. A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer’s disease mice;Acta Biomaterialia;2017-02

5. Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model;The Journal of Neuroscience;2017-01-30

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