Epidermal Bioelectronics for Management of Chronic Diseases: Materials, Devices and Systems

Author:

Qiao Zheng12,Chen Shuwen13,Fan Shicheng1,Xiong Ze13,Lim Chwee Teck12345ORCID

Affiliation:

1. Department of Biomedical Engineering National University of Singapore Singapore 117583 Singapore

2. SIA‐NUS Digital Aviation Corporate Lab National University of Singapore 117602 Singapore Singapore

3. Institute for Health Innovation and Technology (iHealthtech) National University of Singapore Singapore 117599 Singapore

4. Mechanobiology Institute National University of Singapore Singapore 117411 Singapore

5. Institute for Functional Intelligent Materials National University of Singapore Singapore 117544 Singapore

Abstract

AbstractChronic diseases are currently posing a major challenge not only to our life expectancy and healthspan but also to the healthcare system, as patients will need continual monitoring, treatment, and care to mitigate some of the severe health complications that may arise. Merely frequent visits to medical facilities and clinics may not be sufficient. Home‐based point‐of‐care diagnosis and monitoring may be needed for the prevention and/or management of long‐term complications. Recent advances in materials, fabrication methods, and bioelectronics have led to some epidermal systems that can measure critical physiological parameters and provide long‐term monitoring of several chronic diseases. In this review, it is systematically outlined the progress of epidermal bioelectronics aimed at managing common chronic diseases, such as cardiovascular diseases, diabetes, and chronic wounds. Flexible and stretchable materials with related engineering approaches that render wearability are also discussed. Finally, a list of current challenges, future perspectives as well as potential research directions with the aim towards better translation in bringing these wearable technologies from the laboratory to the clinic and market are presented.

Funder

National University of Singapore

National Research Foundation

Publisher

Wiley

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