Protective roles of hepatic gamma-aminobutyric acid signaling in acute ethanol exposure-induced liver injury

Author:

Wang Shuanglian1ORCID,Sui Shaofeng2,Liu Zhiyan3,Peng Cheng4,Liu Jia5,Luo Dan1,Fan Xinhuan1,Liu Chuanyong1,Lu Wei-Yang67

Affiliation:

1. Department of Physiology; Shandong University School of Medicine; Jinan Shandong People's Republic of China

2. Shandong Center for Disease Control and Prevention; Institute of Occupational and Environmental Health; Jinan Shandong People's Republic of China

3. Department of Pathology; Shandong University School of Medicine; Jinan Shandong People's Republic of China

4. Shandong University Qi Lu Hospital; Jinan Shandong People's Republic of China

5. Xinhua Hospital; Huainan Anhui People's Republic of China

6. Department of Physiology and Pharmacology; University of Western Ontario; London ON Canada

7. Robarts Research Institute, University of Western Ontario; London ON Canada

Funder

Canadian Institutes of Health Research

National Natural Science Foundation of China

Publisher

Wiley

Subject

Toxicology

Reference35 articles.

1. Acute ethanol ingestion raises plasma gamma amino-butyric acid levels in healthy men;Bannister;Alcohol and Alcoholism,1988

2. Extrasynaptic GABAA receptors: form, pharmacology, and function;Belelli;Journal of Neuroscience,2009

3. Ethanol Regulation of synaptic GABAA alpha4 receptors is prevented by protein kinase A activation;Carlson;Journal of Pharmacology and Experimental Therapeutics,2016

4. The contribution of endoplasmic reticulum stress to liver diseases;Dara;Hepatology,2011

5. Sensitivity of GABAergic tonic currents to acute ethanol in cerebellar granule neurons is not age- or delta subunit-dependent in developing rats;Diaz;Alcoholism, Clinical and Experimental Research,2016

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