A system using patient-specific 3D-printed molds to spatially align in vivo MRI with ex vivo MRI and whole-mount histopathology for prostate cancer research

Author:

Wu Holden H.12ORCID,Priester Alan23,Khoshnoodi Pooria1,Zhang Zhaohuan12,Shakeri Sepideh1,Afshari Mirak Sohrab1,Asvadi Nazanin H.1,Ahuja Preeti1,Sung Kyunghyun12ORCID,Natarajan Shyam23,Sisk Anthony4,Reiter Robert3,Raman Steven13,Enzmann Dieter1

Affiliation:

1. Department of Radiological Sciences; University of California Los Angeles; Los Angeles California USA

2. Department of Bioengineering; University of California Los Angeles; Los Angeles California USA

3. Department of Urology; University of California Los Angeles; Los Angeles California USA

4. Department of Pathology; University of California Los Angeles; Los Angeles California USA

Funder

Integrated Diagnostics Program, Departments of Radiological Sciences and Pathology, David Geffen School of Medicine at UCLA

Publisher

Wiley

Subject

Radiology Nuclear Medicine and imaging

Reference25 articles.

1. Cancer statistics, 2017;Siegel;CA Cancer J Clin,2017

2. Multiparametric MRI of prostate cancer: an update on state-of-the-art techniques and their performance in detecting and localizing prostate cancer;Hegde;JMagn Reson Imaging,2013

3. Challenges in accurate registration of 3-D medical imaging and histopathology in primary prostate cancer;Meyer;Eur J Nucl Med Mol Imaging,2013

4. Use of patient-specific MRI-based prostate mold for validation of multiparametric MRI in localization of prostate cancer;Trivedi;Urology,2012

5. Magnetic resonance imaging underestimation of prostate cancer geometry: use of patient specific molds to correlate images with whole mount pathology;Priester;JUrol,2017

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