A validated sensitive HPLC-MS/MS method for quantification of a potential hypnotic drug MT502 and its application to a pharmacokinetic study in rat

Author:

Zhang Fang-Fang1,Cheng Ying1,Wan Ning1,Jing Zi-Wei1,Ju Jia1,Jia Yi-Yang1,Zhou Si-Yuan1,Zhang Bang-Le1

Affiliation:

1. Department of Pharmaceutics, School of Pharmacy; Fourth Military Medical University; Xi'an 710032 People's Republic of China

Funder

National Natural Science Foundation of China

National Science & Technology Major Project of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference24 articles.

1. Efficacy of melatonin treatment in jet lag, shift work, and blindness;Arendt;Journal of Biological Rhythms,1997

2. High-performance liquid chromatographic analysis of Peptide T in rabbit plasma with on-line column enrichment;Bechgaard;Journal of Chromatography B, Biomedical Sciences and Applications,1997

3. New insights into melatonin regulation of cancer growth;Blask;Advances in Experimental Medicine and Biology,1999

4. Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin;Bonilla;Experimental Gerontology,2002

5. Melatonin in humans;Brzezinski;The New England Journal of Medicine,1997

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