Getting the Dosage Right: A Vital Role for Clinical Pharmacology in the Era of Precision Medicine

Author:

Minichmayr Iris K.1ORCID,Shebley Mohamad2ORCID,van der Graaf Piet H.34,Venkatakrishnan Karthik5ORCID

Affiliation:

1. Department of Clinical Pharmacology Medical University of Vienna Vienna Austria

2. Clinical Pharmacology, AbbVie Inc. North Chicago Illinois USA

3. Leiden Academic Centre for Drug Research Leiden University Leiden The Netherlands

4. Certara Canterbury UK

5. EMD Serono Research and Development Institute, Inc. Billerica Massachusetts USA

Publisher

Wiley

Reference39 articles.

1. Moving the needle for oncology dose optimization: a call for action;Venkatakrishnan K.;Clin. Pharmacol. Ther.,2024

2. Dosage optimization: a regulatory perspective for developing oncology drugs;Rahman A.;Clin. Pharmacol. Ther.,2024

3. Dose optimization in oncology drug development: an international consortium for innovation and quality in pharmaceutical development white paper;Samineni D.;Clin. Pharmacol. Ther.,2024

4. “Getting the dose right” – revisiting the topic with focus on biologic agents;Mould D.R.;Clin. Pharmacol. Ther.,2024

5. Beyond MABEL: an integrative approach to first in human dose selection of Immunomodulators by the Health and Environmental Sciences Institute (HESI) Immuno‐safety Technical Committee (ITC);Matsumoto M.;Clin. Pharmacol. Ther.,2024

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