MYCN overexpression is associated with unbalanced copy number gain, altered nuclear location, and overexpression of chromosome arm 17q genes in neuroblastoma tumors and cell lines
Author:
Affiliation:
1. Manitoba Institute of Cell Biology, University of Manitoba, CancerCare Manitoba; Winnipeg MB Canada
2. Department of Pathology; University of Manitoba, Health Sciences Centre; Winnipeg MB Canada
Funder
CIHR
Publisher
Wiley
Subject
Cancer Research,Genetics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/gcc.22273/fullpdf
Reference42 articles.
1. Prognostic significance of MYCN oncogene expression in childhood neuroblastoma;Bordow;J Clin Oncol,1998
2. Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma;Bown;N Engl J Med,1999
3. Comparative genomic hybridization (CGH) analysis of neuroblastomas-An important methodological approach in paediatric tumour pathology;Brinkschmidt;J Pathol,1997
4. Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma;Caron;Med Pediatr Oncol,1995
5. MYCN protein expression as a predictor of neuroblastoma prognosis;Chan;Clin Cancer Res,1997
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