Physical compensation method for dispersion of multiple materials in swept source optical coherence tomography

Author:

Huang Jiangjie12ORCID,Fan Jinyu12,He Yi12,Shi Guohua1234

Affiliation:

1. School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine University of Science and Technology of China Hefei China

2. Jiangsu Key Laboratory of Medical Optics Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences Suzhou China

3. Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences Shanghai China

4. Key Laboratory of Myopia of State Health Ministry Key Laboratory of Visual Impairment and Restoration of Shanghai Shanghai China

Abstract

AbstractAn ophthalmic swept source‐optical coherence tomography (SS‐OCT) system based on a high‐speed scanning laser at 1060 nm with a scanning rate of 100 KHz is constructed. Since the sample arm of the interferometer is comprised of multiple glass materials, the ensuing dispersion severely degrades imaging quality. In this article, second‐order dispersion simulation analysis for various materials was performed first, and dispersion equilibrium was implemented utilizing physical compensation methods. After dispersion compensation, an imaging depth in air of 4.013 mm was achieved in model eye experiments, and signal‐to‐noise ratio was enhanced by 11.6%, with a value of 53.8 dB. In vivo imaging of the human retina was performed to demonstrate structurally distinguishable retinal images, characterized by an axial resolution improvement of 19.8%, with a value of 7.7 μm close to the theoretical value of 7.5 μm. The proposed physical dispersion compensation method enhances imaging performance in SS‐OCT systems, enabling visualization of several low scattering mediums.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,General Biochemistry, Genetics and Molecular Biology,General Materials Science,General Chemistry

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Robust and automated dispersion compensation for FD-OCT using fractional Fourier transform;Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII;2024-03-13

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