Two‐dimensional elastic distribution imaging of the sclera using acoustic radiation force optical coherence elastography

Author:

Luo Jiahui1,Zhang Yubao1ORCID,Ai Sizhu1,Shi Gang1,Han Xiao1,Wang Yidi1,Zhao Yanzhi2,Yang Hongwei2,Li Yingjie3,He Xingdao1

Affiliation:

1. Key Laboratory of Opto‐Electronic Information Science and Technology of Jiangxi Province and Jiangxi Engineering Laboratory for Optoelectronics Testing Technology Nanchang Hangkong University Nanchang PR China

2. Eye Center Second Affiliated Hospital of Nanchang University Nanchang PR China

3. Department of Ophthalmology, Nanchang First Hospital Nanchang PR China

Abstract

AbstractThe scleral elasticity is closely related with many ocular diseases, but the relevant research is still insufficient. Here, we utilized optical coherence elastography to carefully study biomechanical properties of the sclera at different positions and under different intraocular pressures. Meanwhile, elastic wave velocity and Young's modulus of each position were obtained using a phase velocity algorithm. Accordingly, the two‐dimensional elasticity distribution image was achieved by mapping the Young's modulus values to the corresponding structure based on the relationship between the position and its Young's modulus. Therefore, elastic information in regions‐of‐interest can be read and compared directly from the scleral structure, indicating that our method may be a very useful tool to evaluate the elasticity of sclera and provide intuitive and reliable proof for diagnosis and research.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,General Biochemistry, Genetics and Molecular Biology,General Materials Science,General Chemistry

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